CEU COURSE: WARM AUTOANTIBODIES

Although warm autoantibodies may not be encountered frequently during pre-transfusion testing, when they are, they present a challenge for providing units of Red Blood Cells. This presentation reviews the serologic techniques used to detect alloantibodies when autoantibodies are present and provision of Red Blood Cells for these types of challenging patient samples.

TARGET AUDIENCE: Technologists, Technicians, Laboratory Managers

LEVEL: Intermediate

SUCCESSSM CREDITS: 1.0 CEU

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LEARNING OBJECTIVES
At the conclusion of this course, participants should be able to:

  1. Describe typical warm autoantibody serological findings.
  2. Apply serological techniques to detect alloantibodies when a warm antibody is present.
  3. Describe selection of units of red blood cells for transfusion.

LEARNING TASKS
To receive CEU credit for this course, participants must:

  1. Review the presentation "Warm Autoantibodies," or read the PowerPoint slides and accompanying notes available as a printable Adobe ReaderĀ® file.
  2. Take the online Post-Test.
  3. Complete the online Course Evaluation.
  4. Print the certificate awarding 1.0 SUCCESSSM program CEU.

FACULTY
Joanne Kosanke,MT(ASCP)SBB
Director, Immunohematology Reference Laboratory
American Red Cross Biomedical Services, Central Ohio Region

LEARNING REFERENCES

  1. Garratty G. Immune hemolytic anemia associated with drug therapy. Blood Reviews 2010;24:143-150
  2. RR Gammon et al. Use of EGA treated neocytes allowed phenotyping of DAT positive samples from patients not recently transfused (abstract). Transfusion 2006; 132A
  3. Leger RM, Garratty G. Evaluation of methods for detecting alloantibodies underlying warm autoantibodies. Transfusion 1999;39:11-16
  4. McConnell G et al. Warm autoantibody adsorption time may be successfully shortened to 15 minutes. Transfusion 2008;48 SOP41
  5. Prophylactic antigen-matched donor blood for patients with warm autoantibodies: an algorithm for transfusion management. Transfusion 2002;42:1435-1441

DISCLAIMER
The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of the American Red Cross Biomedical Services. Information herein is presented for educational purposes and not to endorse off-label use. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings.

RELEASE DATE: 07/09/2015

REVIEW DATE: 07/08/2017

EXPIRATION DATE: 07/08/2019

ESTIMATED TIME TO COMPLETE ACTIVITY:
1 hour

Last modified: Wednesday, August 8, 2018, 02:20 PM