CEU COURSE: Massive Transfusion Protocols: Current Practices and New Innovations for Managing Traumatic Hemorrhage

Massive transfusion practices have changed considerably in the last several years from primarily laboratory-guided therapy to formula-driven protocols. In this program, the rationale for developing massive transfusion protocols will be reviewed. The evidence in the literature supporting and refuting the use of high ratios of plasma to red blood cells will also be discussed. Lastly, new ideas and products that should be considered for use in a massive transfusion protocol will be described. There are no participant prerequisites for this activity. The result of the PROPPR study was published in JAMA in 2015 (JAMA 2015; 313(5): 471-482). There were no significant differences in the primary outcomes of 24-hour and 30-day all-cause mortality between the 1:1:1 group and the 1:1:2 group. Death due to exsanguination was decreased in the 1:1:1 group and more patients in that group achieved hemostasis. No other safety differences between the two groups was noted.

TARGET AUDIENCE: Technologists, technicians and laboratory managers. 

LEVEL: Intermediate 


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At the conclusion of this course, participants should be able to:

  1. Define a Massive Transfusion and describe the important elements required in creating a massive transfusion protocol (MTP).
  2. Discuss the proven and controversial aspects of blood product ratios in formula-driven MTPs. Describe the advantages and challenges in using Group A plasma for trauma resuscitation.
  3. Identify 'new' blood products such as whole blood and cold-stored platelets that may be beneficial for use in trauma resuscitation.

To receive CEU credit for this course, participants must:

  1. Review the presentation "Massive Transfusion Protocols: The Rationale for Ratios and the Impact on Patients" or read the PowerPoint slides and accompanying notes available as a printable Adobe Reader® file.
  2. Take the online Post-Test.
  3. Complete the online Course Evaluation.
  4. Print the certificate awarding 1.0 CEU SUCCESS CEU Credit through the SUCCESSTM program.

P. Dayand Borge MD, PhD
Divisional Chief Medical Officer, American Red Cross Blood Services
East Division
Baltimore, MD

The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of the American Red Cross Biomedical Services. Information herein is presented for educational purposes only.

RELEASE DATE: 11/30/2018


1.0 hour
Last modified: Thursday, July 11, 2019, 03:20 PM